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- 品牌:Invivogen
- 產(chǎn)地:國(guó)外
- 型號(hào):詳詢(xún)
- 貨號(hào):bb-ifnt1
- 發(fā)布日期: 2023-03-30
- 更新日期: 2024-08-12
產(chǎn)地 | 國(guó)外 |
保存條件 | -20℃保存 |
品牌 | Invivogen |
貨號(hào) | bb-ifnt1 |
用途 | 科研 |
組織來(lái)源 | 詳詢(xún) |
細(xì)胞形態(tài) | 詳詢(xún) |
是否是腫瘤細(xì)胞 | 是 |
保質(zhì)期 | 詳詢(xún) |
器官來(lái)源 | 詳詢(xún) |
免疫類(lèi)型 | 詳詢(xún) |
品系 | 詳詢(xún) |
生長(zhǎng)狀態(tài) | 詳詢(xún) |
物種來(lái)源 | 詳詢(xún) |
包裝規(guī)格 | 詳詢(xún) |
是否進(jìn)口 | 是 |
Cell line description:
B16-Blue™ IFN-α/β cells derive from the murine B16 melanoma cell line of C57BL/6 origin after stable transfection with a SEAP (secreted embryonic alkaline phosphatase) reporter gene under the control of the IFN-α/β-inducible ISG54 promoter enhanced by a multimeric ISRE. These cells do not respond to IFN-γ, due to the inactivation of the IFN-γ receptor.
B16-Blue™ IFN-α/β cells respond specifically to mIFN-α/β and do not respond to human IFN-α/β. Stimulation of these cells with murine IFN-α or IFN-β, or type I IFN inducers, such as poly(I:C), poly(dA:dT) or 5’ppp-dsRNA delivered intracellularly, triggers the production of SEAP by the activation of the IRF-inducible promoter. Levels of SEAP can be easily monitored using the detection medium QUANTI-Blue™ Solution.